406 Ventures Safe Fifth Fund, Eyes Future Startups


Boston-based enterprise firm, 406 Ventures, marks one other success story because it gathers substantial assist for its fifth fund. Management of the agency, based by Liam Donohue, Maria Cirino, and Larry Begley, stays rooted within the healthcare, knowledge and AI, and cybersecurity sectors.

The agency’s imaginative and prescient has as soon as once more drawn the eye of each loyal and new buyers. The triple experience of Donohue, Cirino, and Begley not solely underpins the agency’s strategic investments, but additionally conjures up belief.

Modern startups in healthcare, knowledge and AI, and cybersecurity domains can count on 406 Ventures to maintain scouting for promising prospects. The agency’s confirmed technique usually yields excessive returns, paving a profitable path for future ventures. It’s these new funds that can gasoline future progress and improvements.

The fifth fund represents quite a lot of contributors like college endowments, foundations, pension schemes, and strategic buyers. The agency, now 18 years robust, has efficiently raised over $1.4 billion of whole capital. This capital is allotted amongst 5 major funds and three alternative funds.

Liam Donohue famous an uptick in repeat founders looking forward to investments, a development set to proceed within the fifth fund. One in three investments in Fund 4 was with a serial entrepreneur.

Amongst its portfolio of 87 firms, 406 Ventures proudly contains many profitable exits or public listings. One such instance is Iora Well being, now a part of Amazon Well being after being purchased out by OneMedical. There’s additionally a cybersecurity insurance coverage firm bought by Vacationers again in 2023.

The brand new fund already boosts 4 firms, for instance Portrait Analytics, an AI platform for funding analysis, and thesis era. Projections point out over 20 firms will reap the advantages of this fund.

406 Ventures strives to reduce startup funding threat. With the enter of 100+ C-suite executives from Fortune 500 firms, they determine attainable vulnerabilities and choose startups with safe safeguards. They give the impression of being ahead, creating methods for the subsequent three to 5 years and searching for potential weaknesses.



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